5-Amino-1MQ (5-Amino-1-methylquinolinium) is a small-molecule inhibitor of nicotinamide N-methyltransferase (NNMT), an enzyme involved in one-carbon metabolism and the NAD⁺ salvage pathway. Published in vitro research has examined its effects on NNMT enzymatic activity and downstream modulation of S-adenosylmethionine (SAM) availability in metabolic cell line studies. Additional preclinical studies have characterized its influence on intracellular NAD⁺ precursor flux in adipocyte and skeletal muscle model systems.
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Class: NNMT Inhibitor / NAD⁺ Pathway Modulator | CAS: 1390656-00-4 | Purity: ≥98% (HPLC)
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Format: Lyophilized powder | Storage: −20°C, desiccated, protected from light
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⚠️ Research Use Only. This compound is intended exclusively for qualified in vitro and laboratory research. It is not approved for human consumption, is not a dietary supplement, and has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease or health condition. Researchers are solely responsible for compliance with all applicable federal, state, and local laws governing research chemical use.
