SS-31 (Elamipretide) is a mitochondria-targeted tetrapeptide that selectively accumulates at the inner mitochondrial membrane through electrostatic interaction with cardiolipin, a phospholipid critical to electron transport chain organization. Published in vitro research has characterized its role in stabilizing cristae architecture and reducing electron leak-associated reactive oxygen species (ROS) production in isolated mitochondrial preparations. Animal model studies have further examined its effects on ATP synthesis efficiency and mitochondrial membrane potential under oxidative stress conditions in preclinical research settings.
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Class: Mitochondria-Targeted Tetrapeptide / Cardiolipin Stabilizer | Sequence: D-Arg-dimethylTyr-Lys-Phe-NH₂
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CAS: 736992-21-5 | MW: 639.8 g/mol | Purity: ≥98% (HPLC) | Format: Lyophilized powder
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Storage: −20°C, desiccated, protected from light | Reconstitution: Bacteriostatic water recommended for research use
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⚠️ Research Use Only. This compound is intended exclusively for qualified in vitro and laboratory research. It is not approved for human consumption, is not a dietary supplement, and has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease or health condition. Researchers are solely responsible for compliance with all applicable federal, state, and local laws governing research chemical use.
